HPE ProLiant DL380 Gen11 Server with Intel Xeon Silver 4410Y, 32GB DDR5 RAM, MR408i-o Storage Controller, 8 SFF Drive Support (P52560-421)
HPE ProLiant DL380 Gen11 Server is a versatile and high-performance 2U rack server designed to support demanding enterprise workloads, virtualization platforms, and data-intensive applications. Powered by the Intel Xeon Silver 4410Y processor and equipped with 32GB of DDR5 ECC memory, this server delivers reliable performance, improved bandwidth, and enhanced system stability for modern data centers. It features the HPE MR408i-o Gen11 storage controller with 4GB cache, enabling advanced hardware RAID capabilities and optimized storage performance. With support for up to eight Small Form Factor drives, four efficient cooling fans, and a 1000W Flex Slot Titanium hot-plug power supply, the DL380 Gen11 offers scalable storage, energy-efficient operation, and enterprise-grade reliability. Combined with HPE’s advanced security architecture and integrated remote management tools, this server is an ideal solution for businesses seeking a secure, scalable, and powerful infrastructure platform.
Product Features
Intel Xeon Silver 4410Y Processor for Enterprise Performance
The Intel Xeon Silver 4410Y processor delivers strong performance for virtualization, database management, and enterprise applications. Built on Intel’s latest server architecture, it offers improved efficiency, multi-core processing capability, and enhanced workload performance for modern IT environments.
32GB DDR5 ECC Registered Memory
The server includes 32GB of DDR5 ECC Registered DIMM memory, delivering higher bandwidth and improved efficiency compared to previous memory generations. Error-correcting technology helps detect and correct memory errors to maintain system stability and protect data integrity.
HPE MR408i-o Gen11 Storage Controller with 4GB Cache
The HPE MR408i-o Gen11 storage controller provides hardware-based RAID functionality and includes 4GB of onboard cache for improved storage performance. It supports advanced RAID levels that enhance data protection, availability, and overall storage efficiency.
Support for Eight Small Form Factor Drives
With support for up to eight SFF drives, the DL380 Gen11 allows organizations to configure high-performance SSDs or high-capacity HDDs depending on business requirements. This flexibility supports scalable storage infrastructure for growing workloads.
Energy Efficient 1000W Flex Slot Titanium Power Supply
The 1000W Flex Slot Titanium hot-plug power supply delivers highly efficient power conversion, reducing energy consumption while maintaining reliable server operation. Titanium-rated efficiency helps minimize operating costs in enterprise environments.
Advanced Cooling with Four Standard Fans
The system includes four high-efficiency standard fans that ensure proper airflow and thermal management. This cooling architecture maintains stable performance even during heavy workloads.
Scalable 2U Rackmount Design
The 2U rack design provides excellent scalability for storage, networking, and expansion cards, making the server suitable for evolving data center and enterprise infrastructure requirements.
HPE Silicon Root of Trust Security
HPE’s Silicon Root of Trust technology protects the server firmware from unauthorized access and tampering. This security architecture ensures the system boots from trusted firmware and maintains platform integrity.
Integrated HPE iLO Remote Management
HPE Integrated Lights-Out management provides secure remote monitoring, server configuration, firmware updates, and troubleshooting, allowing IT administrators to efficiently manage infrastructure from anywhere.
Optimized for Virtualization and Enterprise Workloads
The DL380 Gen11 platform is designed to support virtualization platforms, enterprise databases, cloud environments, and mission-critical applications requiring consistent performance and reliability.
Product Specifications
- Product model: HPE ProLiant DL380 Gen11 Server
- Part number: P52560-421
- Form factor: 2U rackmount server
- Processor: Intel Xeon Silver 4410Y
- Processor cores: 12 cores
- Processor threads: 24 threads
- Processor base frequency: 2.0 GHz
- Processor turbo frequency: Up to 3.9 GHz
- Cache: 30 MB Intel Smart Cache
- Memory installed: 32 GB (1 x 32 GB) DDR5 ECC Registered DIMM
- Memory rank: Dual Rank
- Memory type: DDR5 ECC RDIMM
- Maximum memory capacity: Up to 8 TB depending on configuration
- Storage controller: HPE MR408i-o Gen11 x8 Lanes Storage Controller
- Controller cache: 4 GB cache
- RAID levels supported: 0, 1, 5, 6, 10, 50, 60
- Drive support: Up to 8 Small Form Factor drives
- Drive interface: SAS, SATA, or NVMe depending on configuration
- Cooling: Four standard system fans
- Power supply: HPE 1000W Flex Slot Titanium Hot Plug Power Supply
- Power supply efficiency: Titanium rated efficiency
- Expansion slots: PCIe Gen5 expansion slots
- Network interface: Integrated HPE networking support
- Management: HPE Integrated Lights-Out (iLO) server management
- Security features: Silicon Root of Trust, secure boot, firmware protection
- Warranty: 3 years parts, 3 years labor, 3 years onsite support (3/3/3 warranty)







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